Portland:
Cascade Brewing Barrel House-specialize in sour beers but make some good regulars beers as well. Spring Gose comes out today03-18-2011 - this light, slightly soured beer is spiced with sea salt, wild chamomile, lemon peel and culinary lavender. have to try Bourbonic Plague
This blend of strong dark porters was aged in oak, wine and Bourbon barrels, then blended with a dark porter that had been brewed with vanilla beans and cinnamon. The blend was then aged an additional 14 months on dates. IF THEY HAVE IT ON TAP
Bridgeport Brewery & Restaurant
Deschutes Brewery & Restaurant-Best pretzel in Portland and really good beer to boot.
Rogue
Amnesia-832 North Beech Street. Good place for a sausage dog if its not raining at night. Weather been sucking here lately.
Full Sail-307 Southwest Montgomery Street. They do special taps hear
Up Right Brewing-240 N. Broadway, Suite 002 they make some good beers
Prost- Its a bar but if you want to meet Das Boot(1L & 2L) you have to go here.
http://prostportland.com/ On Mississippi
Seattle:The breweries below are my 2 favorite in Seattle. Although Red Hook in Woodinville is good to.
Mac & Jacks-
http://www.macandjacks.com/index.php . One of my favorites. Can only get there beer on tap. Go by the brewery and taste their beers though. You get to keep the pint glass.
Black Raven Brewery
http://www.blackravenbrewing.com - A new brewery and it's fantastic. I try and go to the brewery every time I drive up to see the in-laws. I bring back a growler or two when I visit them. Try the La Petite Mort, Trickster IPA, and their porter. They still might have their Coco Jones Coconut Brown porter on tap. They tapped it March 15. I sure wish you could bring me down a growler to Portland.
Both Mac & Jacks and Black Raven are fairly close to each other. They are in Redmond Washington goodluck drinking and finding new beers. I hope that your visit up here is great.