Don't know about brew pubs, etc., but if you never had any before you should try as much New Belgium Beer as you can..
Fat Tire and 1554 are my favorites, but they have many good ones, and you can't get them on the East Coast...
http://www.newbelgium.com
I know that Quark's Bar in the Start Trek Experience at the Hilton has fat Tire, but they call it by some Trekkie name... If you don't mind hanging with Klingon's, Borg and geeks it's a fun thing to see...
Have fun..